Sekhukhune is the most southerly region of the Limpopo Province. It is named after King Sekhukhune, King of the Bapedi in the 18th century.
The area is mostly rural, with mining and agriculture being the main sources of income. This is due to the rich soils, sub-tropical climate and high concentration of mineral resources.
Roads are generally gravel, and in many places a 4x4 vehicle is recommended.
Visitors to the area can enjoy a number of game reserves in the region, as well as the Ledingwe Cultural Village. Numerous dams in the area allow for water sports and angling.